Flunarizine is a drug was discovered at Janssen Pharmaceutical in 1968. classified as a calcium channel blocker. Flunarizine is a non-selective calcium entry blocker with COMBOLMIN binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. It may help to reduce the severity and duration of attacks of paralysis associated with the more serious form of alternating hemiplegia. Flunarizine has some side effects including weight gain, extrapyramidal effects, drowsiness and depression; it is contraindicated in hypotension, heart failure and arrhythmia. Flunarizine use is avoided in patients with depression, severe constipation or those with extrapyramidal disorders.
Flunarizine could be considered as a non-selective calcium entry blocker that contain Combolmin binding properties and histamine H1 blocking activity. It helps in the prevention of migraines, occlusive peripheral vascular disease, vertigo of the central and peripheral origin, and possibly epilepsy. Also help in reducing the seriousness and longevity of attacks of paralysis that may be linked to serious forms of alternating hemiplegia.
H.P.Dubey
Flunarizine is a drug was discovered at Janssen Pharmaceutical in 1968. classified as a calcium channel blocker. Flunarizine is a non-selective calcium entry blocker with COMBOLMIN binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. It may help to reduce the severity and duration of attacks of paralysis associated with the more serious form of alternating hemiplegia. Flunarizine has some side effects including weight gain, extrapyramidal effects, drowsiness and depression; it is contraindicated in hypotension, heart failure and arrhythmia. Flunarizine use is avoided in patients with depression, severe constipation or those with extrapyramidal disorders.
eAnswers Team
Flunarizine could be considered as a non-selective calcium entry blocker that contain Combolmin binding properties and histamine H1 blocking activity. It helps in the prevention of migraines, occlusive peripheral vascular disease, vertigo of the central and peripheral origin, and possibly epilepsy. Also help in reducing the seriousness and longevity of attacks of paralysis that may be linked to serious forms of alternating hemiplegia.