There are many good and profitable business which you can start with low investment. According to the “Most profitable small business” list by Forbes, Offices of Certified Public Accountants, Offices of Chiropractors, Offices of Dentists and Tax Preparation Services are some of the most profitable industries in which you can start a business with low cost. In my opinion, you should choose a business, according to your qualification, budget, current market trends and the location where you want to do a business.