Yes, the ozone layer can repair itself by the natural cycle. The ozone layer mainly includes molecules of oxygen and nitrogen. According to a research, 50% of the ozone layer can repair itself in just 10 years if we remove all the contaminants (CFC), but the recovering stage of the ozone layer will not come in next 15 to 20 years. The human activities have played a crucial role in the depletion of the ozone layer.